{"id":137596,"date":"2020-07-15T06:57:00","date_gmt":"2020-07-14T22:57:00","guid":{"rendered":"http:\/\/4563.org\/?p=137596"},"modified":"2020-07-15T06:57:00","modified_gmt":"2020-07-14T22:57:00","slug":"%e6%9c%89%e6%b2%a1%e6%9c%89%e7%94%a8-r-%e8%af%ad%e8%a8%80%e5%81%9a%e8%bf%87%e7%94%9f%e4%bf%a1%e5%88%86%e6%9e%90%e7%9a%84%e5%a4%a7%e4%bd%ac%e5%95%8a","status":"publish","type":"post","link":"http:\/\/4563.org\/?p=137596","title":{"rendered":"\u6709\u6ca1\u6709\u7528 R \u8bed\u8a00\u505a\u8fc7\u751f\u4fe1\u5206\u6790\u7684\u5927\u4f6c\u554a"},"content":{"rendered":"<div>\n<div>\n<div>\n<h1>                  \u6709\u6ca1\u6709\u7528 R \u8bed\u8a00\u505a\u8fc7\u751f\u4fe1\u5206\u6790\u7684\u5927\u4f6c\u554a               <\/h1>\n<p> <\/p>\n<div>\n<div> <span>\u8cc7\u6df1\u5927\u4f6c : ZZHH1996 <\/span>  <span><i><\/i> 6<\/span> <\/div>\n<div> <\/div>\n<\/p><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<div isfirst=\"1\"> <\/p>\n<p>\u5c0f\u5f1f\u662f\u5c0f\u767d\uff0c\u7528 R \u8bed\u8a00\u7684 edgeR \u5305\u5206\u6790\u4e86\u4ece TCGA \u6570\u636e\u5e93\u91cc\u9762\u4e0b\u8f7d\u7684\u4e00\u4e2a\u80bf\u7624\u7684 count \u6570\u636e\uff0c\u901a\u8fc7 edgeR \u5206\u6790\u786e\u5b9a\u4e86\u4e00\u4e2a logFC=3 \u70b9\u591a\uff0cp&lt;0.001 \u7684\u4e0a\u8c03\u5dee\u5f02\u8868\u8fbe\u57fa\u56e0\uff0c\u7136\u540e\u5462\u60f3\u628a\u5b83\u62ff\u51fa\u6765\u7ee7\u7eed\u7814\u7a76\uff0c\u4e8e\u662f\u628a\u5b83\u5355\u72ec\u62ce\u51fa\u6765\uff0c\u8fd8\u662f\u7528\u524d\u9762\u7684 TCGA \u7684\u6570\u636e\uff0c\u7528\u8fd9\u4e2a\u57fa\u56e0\u5728 500 \u591a\u4e2a\u764c\u75c7\u6837\u672c\u548c 40 \u591a\u4e2a\u6b63\u5e38\u6837\u672c\u4e2d\u7684\u8868\u8fbe\u8fdb\u884c\u6bd4\u8f83\uff0c\u505a\u4e86\u4e00\u4e2a\u5c0f\u63d0\u7434\u56fe\uff0c\u51fa\u73b0\u95ee\u9898\u4e86\uff0c\u53d1\u73b0\u505a\u51fa\u5c0f\u63d0\u7434\u56fe\u6765\u4ee5\u540e\u8fd9\u4e2a\u57fa\u56e0\u5728\u764c\u75c7\u7ec4\u548c\u6b63\u5e38\u7ec4\u91cc\u9762\u7684\u8868\u8fbe\u6ca1\u6709\u5dee\u5f02\uff0cp=0.58 \u3002\u5404\u4f4d\u5927\u4f6c\uff0c\u4e3a\u4ec0\u4e48\u4f1a\u51fa\u73b0\u8fd9\u79cd\u60c5\u51b5\uff0c\u662f\u6570\u636e\u5206\u6790\u6709\u9519\uff0c\u8fd8\u662f\u56e0\u4e3a edgeR \u548c\u5c0f\u63d0\u7434\u56fe\u7684 Wilcox \u68c0\u9a8c\u7684\u7b97\u6cd5\u4e0d\u540c\u9020\u6210\u7684\uff1f\u8fd9\u6837\u5230\u5e95\u7b97\u5b83\u662f\u4e0d\u662f\u5dee\u5f02\u57fa\u56e0\u554a\uff1f \u8fd8\u6709\u5c31\u662f\u6211\u7528 TCGA \u6570\u636e\u91cc 40 \u591a\u4e2a\u6b63\u5e38\u6837\u672c\uff0c\u627e\u5230\u4ed6\u4eec\u914d\u5bf9\u7684\u764c\u75c7\u6837\u672c\uff0c\u5bf9\u8fd9\u4e2a\u57fa\u56e0\u7684\u8868\u8fbe\u5728\u8fd9\u4e24\u7ec4\u8fdb\u884c\u914d\u5bf9 t \u68c0\u9a8c\uff0c\u53d1\u73b0\u662f\u6709\u610f\u4e49\u7684\u4e0a\u8c03\u3002<\/p>\n<\/p><\/div>\n<div> <b>\u5927\u4f6c\u6709\u8a71\u8aaa<\/b> (<span>1<\/span>)        <\/div>\n<div> <\/div>\n<\/p><\/div>\n<\/p><\/div>\n<ul>\n<li data-pid=\"2588134\" data-uid=\"2\">\n<div>\n<div>\n<div> <span>\u4e3b<\/span> <span>\u8cc7\u6df1\u5927\u4f6c : ZZHH1996 <\/span>  <\/div>\n<div> <i title=\"\u5f15\u7528\"><\/i>  <span>          <\/span> <\/div>\n<\/p><\/div>\n<div>                                                             \u6709\u6ca1\u6709\u7528 R \u505a\u8fc7\u8fd9\u65b9\u9762\u7684\u5927\u624b\u5b50\u53ef\u4ee5\u6307\u70b9\u4e00\u4e0b                                                            <\/div>\n<\/p><\/div>\n<\/li>\n<li>\n","protected":false},"excerpt":{"rendered":"<p>\u6709\u6ca1\u6709\u7528 R \u8bed\u8a00\u505a\u8fc7\u751f\u4fe1\u5206\u6790\u7684\u5927&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[],"tags":[],"_links":{"self":[{"href":"http:\/\/4563.org\/index.php?rest_route=\/wp\/v2\/posts\/137596"}],"collection":[{"href":"http:\/\/4563.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/4563.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/4563.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/4563.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=137596"}],"version-history":[{"count":0,"href":"http:\/\/4563.org\/index.php?rest_route=\/wp\/v2\/posts\/137596\/revisions"}],"wp:attachment":[{"href":"http:\/\/4563.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=137596"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/4563.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=137596"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/4563.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=137596"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}